The dawn of alchemical free-energy methods in biomolecular simulations

@misc{macuglia2025dawnalchemicalfreeenergy,
      title={The dawn of alchemical free-energy methods in biomolecular simulations},
      author={Daniele Macuglia and Giovanni Ciccotti and Benoît Roux},
      year={2025},
      eprint={2510.04917},
      archivePrefix={arXiv},
      primaryClass={physics.comp-ph},
      url={https://arxiv.org/abs/2510.04917},
}