We establish that $E_n$-operads satisfy a rational intrinsic formality theorem for $n\geq 3$. We gain our results in the category of Hopf cooperads in cochain graded dg-modules which defines a model for the rational homotopy of operads in spaces. We consider, in this context, the dual cooperad of the $n$-Poisson operad $\mathsf{Pois}_n^c$, which represents the cohomology of the operad of little $n$-discs $\mathsf{D}_n$. We assume $n\geq 3$. We explicitly prove that a Hopf cooperad in cochain graded dg-modules $\mathsf{K}$ is weakly-equivalent (quasi-isomorphic) to $\mathsf{Pois}_n^c$ as a Hopf cooperad as soon as we have an isomorphism at the cohomology level $H^*(\mathsf{K})\simeq\mathsf{Pois}_n^c$ when $4\nmid n$. We just need the extra assumption that $\mathsf{K}$ is equipped with an involutive isomorphism mimicking the action of a hyperplane reflection on the little $n$-discs operad in order to extend this formality statement in the case $4\mid n$. We deduce from these results that any operad in simplicial sets $\mathsf{P}$ which satisfies the relation $H^*(\mathsf{P},\mathbb{Q})\simeq\mathsf{Pois}_n^c$ in rational cohomology (and an analogue of our extra involution requirement in the case $4\mid n$) is rationally weakly equivalent to an operad in simplicial sets $LG_{\bullet}(\mathsf{Pois}_n^c)$ which we determine from the $n$-Poisson cooperad $\mathsf{Pois}_n^c$. We also prove that the morphisms $\iota: \mathsf{D}_m\rightarrow\mathsf{D}_n$, which link the little discs operads together, are rationally formal as soon as $n-m\geq 2$. These results enable us to retrieve the (real) formality theorems of Kontsevich by a new approach, and to sort out the question of the existence of formality quasi-isomorphisms defined over the rationals (and not only over the reals) in the case of the little discs operads of dimension $n\geq 3$.

Mirror manifolds to toric Calabi-Yau threefolds are encoded in algebraic curves. The quantization of these curves leads naturally to quantum-mechanical operators on the real line. We show that, for a large number of local del Pezzo Calabi-Yau threefolds, these operators are of trace class. In some simple geometries, like local P2, we calculate the integral kernel of the corresponding operators in terms of Faddeev's quantum dilogarithm. Their spectral traces are expressed in terms of multi-dimensional integrals, similar to the state-integrals appearing in three-manifold topology, and we show that they can be evaluated explicitly in some cases. Our results provide further verifications of a recent conjecture which gives an explicit expression for the Fredholm determinant of these operators, in terms of enumerative invariants of the underlying Calabi-Yau threefolds.