Researchers at UCL developed CLADE, an unsupervised deep learning method that super-resolves anisotropic medical images by learning high-resolution features directly from the inherent anisotropy within the input volume, without needing paired training data. CLADE, which employs a modified CycleGAN with weight demodulation and a cycle-consistent gradient mapping loss, consistently outperformed state-of-the-art self-supervised methods in quantitative and qualitative image quality on abdominal MRI and CT.
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