Orthopantomogram (OPGs) and Cone-Beam Computed Tomography (CBCT) are vital for dentistry, but creating large datasets for automated tooth segmentation is hindered by the labor-intensive process of manual instance-level annotation. This research aimed to benchmark and advance semi-supervised learning (SSL) as a solution for this data scarcity problem. We organized the 2nd Semi-supervised Teeth Segmentation (STS 2024) Challenge at MICCAI 2024. We provided a large-scale dataset comprising over 90,000 2D images and 3D axial slices, which includes 2,380 OPG images and 330 CBCT scans, all featuring detailed instance-level FDI annotations on part of the data. The challenge attracted 114 (OPG) and 106 (CBCT) registered teams. To ensure algorithmic excellence and full transparency, we rigorously evaluated the valid, open-source submissions from the top 10 (OPG) and top 5 (CBCT) teams, respectively. All successful submissions were deep learning-based SSL methods. The winning semi-supervised models demonstrated impressive performance gains over a fully-supervised nnU-Net baseline trained only on the labeled data. For the 2D OPG track, the top method improved the Instance Affinity (IA) score by over 44 percentage points. For the 3D CBCT track, the winning approach boosted the Instance Dice score by 61 percentage points. This challenge confirms the substantial benefit of SSL for complex, instance-level medical image segmentation tasks where labeled data is scarce. The most effective approaches consistently leveraged hybrid semi-supervised frameworks that combined knowledge from foundational models like SAM with multi-stage, coarse-to-fine refinement pipelines. Both the challenge dataset and the participants' submitted code have been made publicly available on GitHub (this https URL), ensuring transparency and reproducibility.

Cone-Beam Computed Tomography (CBCT) and Intraoral Scanning (IOS) are essential for digital dentistry, but annotated data scarcity limits automated solutions for pulp canal segmentation and cross-modal registration. To benchmark semi-supervised learning (SSL) in this domain, we organized the STSR 2025 Challenge at MICCAI 2025, featuring two tasks: (1) semi-supervised segmentation of teeth and pulp canals in CBCT, and (2) semi-supervised rigid registration of CBCT and IOS. We provided 60 labeled and 640 unlabeled IOS samples, plus 30 labeled and 250 unlabeled CBCT scans with varying resolutions and fields of view. The challenge attracted strong community participation, with top teams submitting open-source deep learning-based SSL solutions. For segmentation, leading methods used nnU-Net and Mamba-like State Space Models with pseudo-labeling and consistency regularization, achieving a Dice score of 0.967 and Instance Affinity of 0.738 on the hidden test set. For registration, effective approaches combined PointNetLK with differentiable SVD and geometric augmentation to handle modality gaps; hybrid neural-classical refinement enabled accurate alignment despite limited labels. All data and code are publicly available at this https URL to ensure reproducibility.