Star-forming (SF) regions embedded inside giant molecular clouds (GMCs) are potential contributors to Galactic gamma rays. The gamma-ray source 3FHL J1907.0+0713 is detected with a significance of roughly 13
σ in the 0.2
− 300 GeV energy range after the removal of gamma-ray pulsation periods of PSR J1906+0722 from the Fermi-LAT data set of about 10 years. The energy spectrum of 3FHL J1907.0+0713 is best-fitted to a power law model with a spectral index of 2.26
± 0.05. The CO(
J = 1
−0) data taken by NANTEN2 revealed that 3FHL J1907.0+0713 is overlapping with a GMC having a peak velocity of about 38 km s
−1. The best-fitting location of 3FHL J1907.0+0713 is measured to be approximately 0.13 degrees away from the Galactic supernova remnant (SNR) 3C 397 and it overlaps with a star that is associated with a bow-shock nebula. We show that there is no physical connection between 3FHL J1907.0+0713, 3C 397, as well as any positional coincidence with the pulsar. The spectrum of 3FHL J1907.0+0713 is fitting to both hadronic and leptonic gamma-ray emission models and the total luminosity at a distance of 2.6 kpc is calculated to be 1.1
× 10
34 erg s
−1. We also discuss possible SF origins of gamma rays from 3FHL J1907.0+0713, where SNRs, massive protostar outflows, stellar winds from runaway stars, colliding wind binaries, and young stellar clusters are considered as candidate sources.