We compare the mass functions of young star clusters (ages
≤10 Myr) and giant molecular clouds (GMCs) in six galaxies that cover a large range in mass, metallicity, and star formation rate (LMC, M83, M51, NGC 3627, the Antennae, and NGC 3256). We perform maximum-likelihood fits of the Schechter function,
ψ(M)=dN/dM∝Mβexp(−M/M∗), to both populations. We find that most of the GMC and cluster mass functions in our sample are consistent with a pure power-law distribution (
M∗→∞). M51 is the only galaxy that shows some evidence for an upper cutoff (
M∗) in both populations. Therefore, physical upper mass cutoffs in populations of both GMCs and clusters may be the exception rather than the rule. When we perform power-law fits, we find a range of indices
βPL=−2.3±0.3 for our GMC sample and
βPL=−2.0±0.3 for the cluster sample. This result, that
βClusters≈βGMC≈−2, is consistent with theoretical predictions for cluster formation and suggests that the star-formation efficiency is largely independent of mass in the GMCs.