The $\gamma$-ray from Giant molecular clouds (GMCs) is regarded as the most ideal tool to perform in-situ measurement of cosmic ray (CR) density and spectra in our Galaxy. We report the first detection of $\gamma$-ray emissions in the very-high-energy (VHE) domain from the five nearby GMCs with a stacking analysis based on a 4.5-year $\gamma$-ray observation with the Large High Altitude Air Shower Observatory (LHAASO) experiment. The spectral energy distributions derived from the GMCs are consistent with the expected $\gamma$-ray flux produced via CR interacting with the ISM in the energy interval 1 - 100 $~\rm$ TeV. In addition, we investigate the presence of the CR spectral `knee' by introducing a spectral break in the $\gamma$-ray data. While no significant evidence for the CR knee is found, the current KM2A measurements from GMCs strongly favor a proton CR knee located above 0.9$~\rm$ PeV, which is consistent with the latest measurement of the CR spectrum by ground-based experiments.

Medical image registration is critical for clinical applications, and fair benchmarking of different methods is essential for monitoring ongoing progress. To date, the Learn2Reg 2020-2023 challenges have released several complementary datasets and established metrics for evaluations. However, these editions did not capture all aspects of the registration problem, particularly in terms of modality diversity and task complexity. To address these limitations, the 2024 edition introduces three new tasks, including large-scale multi-modal registration and unsupervised inter-subject brain registration, as well as the first microscopy-focused benchmark within Learn2Reg. The new datasets also inspired new method developments, including invertibility constraints, pyramid features, keypoints alignment and instance optimisation.

Continual Test-Time Adaptation (CTTA) is an emerging and challenging task where a model trained in a source domain must adapt to continuously changing conditions during testing, without access to the original source data. CTTA is prone to error accumulation due to uncontrollable domain shifts, leading to blurred decision boundaries between categories. Existing CTTA methods primarily focus on suppressing domain shifts, which proves inadequate during the unsupervised test phase. In contrast, we introduce a novel approach that guides rather than suppresses these shifts. Specifically, we propose $\textbf{C}$ontrollable $\textbf{Co}$ntinual $\textbf{T}$est-$\textbf{T}$ime $\textbf{A}$daptation (C-CoTTA), which explicitly prevents any single category from encroaching on others, thereby mitigating the mutual influence between categories caused by uncontrollable shifts. Moreover, our method reduces the sensitivity of model to domain transformations, thereby minimizing the magnitude of category shifts. Extensive quantitative experiments demonstrate the effectiveness of our method, while qualitative analyses, such as t-SNE plots, confirm the theoretical validity of our approach.

Medical image challenges have played a transformative role in advancing the field, catalyzing algorithmic innovation and establishing new performance standards across diverse clinical applications. Image registration, a foundational task in neuroimaging pipelines, has similarly benefited from the Learn2Reg initiative. Building on this foundation, we introduce the Large-scale Unsupervised Brain MRI Image Registration (LUMIR) challenge, a next-generation benchmark designed to assess and advance unsupervised brain MRI registration. Distinct from prior challenges that leveraged anatomical label maps for supervision, LUMIR removes this dependency by providing over 4,000 preprocessed T1-weighted brain MRIs for training without any label maps, encouraging biologically plausible deformation modeling through self-supervision. In addition to evaluating performance on 590 held-out test subjects, LUMIR introduces a rigorous suite of zero-shot generalization tasks, spanning out-of-domain imaging modalities (e.g., FLAIR, T2-weighted, T2*-weighted), disease populations (e.g., Alzheimer's disease), acquisition protocols (e.g., 9.4T MRI), and species (e.g., macaque brains). A total of 1,158 subjects and over 4,000 image pairs were included for evaluation. Performance was assessed using both segmentation-based metrics (Dice coefficient, 95th percentile Hausdorff distance) and landmark-based registration accuracy (target registration error). Across both in-domain and zero-shot tasks, deep learning-based methods consistently achieved state-of-the-art accuracy while producing anatomically plausible deformation fields. The top-performing deep learning-based models demonstrated diffeomorphic properties and inverse consistency, outperforming several leading optimization-based methods, and showing strong robustness to most domain shifts, the exception being a drop in performance on out-of-domain contrasts.

Continual Test-Time Adaptation (CTTA) aims to adapt models to sequentially changing domains during testing, relying on pseudo-labels for self-adaptation. However, incorrect pseudo-labels can accumulate, leading to performance degradation. To address this, we propose a Conformal Uncertainty Indicator (CUI) for CTTA, leveraging Conformal Prediction (CP) to generate prediction sets that include the true label with a specified coverage probability. Since domain shifts can lower the coverage than expected, making CP unreliable, we dynamically compensate for the coverage by measuring both domain and data differences. Reliable pseudo-labels from CP are then selectively utilized to enhance adaptation. Experiments confirm that CUI effectively estimates uncertainty and improves adaptation performance across various existing CTTA methods.

Based on the $(2712.4\pm14.4)\times 10^{6}$ $\psi(3686)$ events collected with the BESIII detector, we present a high-precision study of the $\pi^+\pi^-$ mass spectrum in $\psi(3686)\rightarrow\pi^{+}\pi^{-}J/\psi$ decays. A clear resonance-like structure is observed near the $\pi^+\pi^-$ mass threshold for the first time. A fit with a Breit-Wigner function yields a mass of $285.6\pm 2.5~{\rm MeV}/c^2$ and a width of $16.3\pm 0.9~{\rm MeV}$ with a statistical significance exceeding 10$\sigma$. To interpret the data, we incorporate final-state interactions (FSI) within two theoretical frameworks: chiral perturbation theory (ChPT) and QCD multipole expansion (QCDME). ChPT describes the spectrum above 0.3 GeV/$c^2$ but fails to reproduce the threshold enhancement. In contrast, the QCDME model, assuming the $\psi(3686)$ is an admixture of S- and D-wave charmonium, reproduces the data well. The pronounced dip near 0.3 GeV/$c^2$ offers new insight into the interplay between chiral dynamics and low-energy QCD.

Self-orthogonal codes are a significant class of linear codes in coding theory and have attracted a lot of attention. In \cite{HLL2023Te,LH2023Se}, $p$-ary self-orthogonal codes were constructed by using $p$-ary weakly regular bent functions, where $p$ is an odd prime. In \cite{WH2023Se}, two classes of non-degenerate quadratic forms were used to construct $q$-ary self-orthogonal codes, where $q$ is a power of a prime. In this paper, we construct new families of $q$-ary self-orthogonal codes using vectorial dual-bent functions. Some classes of at least almost optimal linear codes are obtained from the dual codes of the constructed self-orthogonal codes. In some cases, we completely determine the weight distributions of the constructed self-orthogonal codes. From the view of vectorial dual-bent functions, we illustrate that the works on constructing self-orthogonal codes from $p$-ary weakly regular bent functions \cite{HLL2023Te,LH2023Se} and non-degenerate quadratic forms with $q$ being odd \cite{WH2023Se} can be obtained by our results. We partially answer an open problem on determining the weight distribution of a class of self-orthogonal codes given in \cite{LH2023Se}. As applications, we construct new infinite families of at least almost optimal $q$-ary linear complementary dual codes (for short, LCD codes) and quantum codes.

The Dark Matter Particle Explorer (DAMPE) is a satellite-borne detector designed to detect high-energy cosmic ray particles with its core component being a BGO calorimeter capable of measuring energies from $\sim$GeV to $O(100)$ TeV. The 32 radiation lengths thickness of the calorimeter is designed to ensure full containment of showers produced by cosmic ray electrons and positrons (CREs) and $\gamma$-rays at energies below tens of TeV, providing high resolution in energy measurements. The absolute energy scale therefore becomes a crucial parameter for precise measurements of the CRE energy spectrum. The geomagnetic field induces a rapid drop in the low energy spectrum of electrons and positrons, a phenomenon that provides a method to determine the calorimeter's absolute energy scale. By comparing the cutoff energies of the measured spectra of CREs with those expected from the International Geomagnetic Reference Field model across 4 McIlwain $L$ bins - which cover most regions of the DAMPE orbit - we find that the calorimeter's absolute energy scale exceeds the calibration based on Geant4 simulation by $1.013\pm0.012_{\rm stat}\pm0.026_{\rm sys}$ for energies between 7 GeV and 16 GeV. The absolute energy scale should be taken into account when comparing the absolute CREs fluxes among different detectors.

Recently, intelligent analysis of lung nodules with the assistant of computer aided detection (CAD) techniques can improve the accuracy rate of lung cancer diagnosis. However, existing CAD systems and pulmonary datasets mainly focus on Computed Tomography (CT) images from one single period, while ignoring the cross spatio-temporal features associated with the progression of nodules contained in imaging data from various captured periods of lung cancer. If the evolution patterns of nodules across various periods in the patients' CT sequences can be explored, it will play a crucial role in guiding the precise screening identification of lung cancer. Therefore, a cross spatio-temporal lung nodule dataset with pathological information for nodule identification and diagnosis is constructed, which contains 328 CT sequences and 362 annotated nodules from 109 patients. This comprehensive database is intended to drive research in the field of CAD towards more practical and robust methods, and also contribute to the further exploration of precision medicine related field. To ensure patient confidentiality, we have removed sensitive information from the dataset.

Accurate classification of fine-grained images remains a challenge in backbones based on convolutional operations or self-attention mechanisms. This study proposes novel dual-current neural networks (DCNN), which combine the advantages of convolutional operations and self-attention mechanisms to improve the accuracy of fine-grained image classification. The main novel design features for constructing a weakly supervised learning backbone model DCNN include (a) extracting heterogeneous data, (b) keeping the feature map resolution unchanged, (c) expanding the receptive field, and (d) fusing global representations and local features. Experimental results demonstrated that using DCNN as the backbone network for classifying certain fine-grained benchmark datasets achieved performance advantage improvements of 13.5--19.5% and 2.2--12.9%, respectively, compared to other advanced convolution or attention-based fine-grained backbones.

Self-orthogonal codes are a significant class of linear codes in coding theory and have attracted a lot of attention. In \cite{HLL2023Te,LH2023Se}, $p$-ary self-orthogonal codes were constructed by using $p$-ary weakly regular bent functions, where $p$ is an odd prime. In \cite{WH2023Se}, two classes of non-degenerate quadratic forms were used to construct $q$-ary self-orthogonal codes, where $q$ is a power of a prime. In this paper, we construct new families of $q$-ary self-orthogonal codes using vectorial dual-bent functions. Some classes of at least almost optimal linear codes are obtained from the dual codes of the constructed self-orthogonal codes. In some cases, we completely determine the weight distributions of the constructed self-orthogonal codes. From the view of vectorial dual-bent functions, we illustrate that the works on constructing self-orthogonal codes from $p$-ary weakly regular bent functions \cite{HLL2023Te,LH2023Se} and non-degenerate quadratic forms with $q$ being odd \cite{WH2023Se} can be obtained by our results. We partially answer an open problem on determining the weight distribution of a class of self-orthogonal codes given in \cite{LH2023Se}. As applications, we construct new infinite families of at least almost optimal $q$-ary linear complementary dual codes (for short, LCD codes) and quantum codes.

Using $20.3~\mathrm{fb}^{-1}$ of $e^+e^-$ collision data collected at a center-of-mass energy of $E_{\rm c.m.}=3.773$ GeV with the BESIII detector operating at the BEPCII collider, we determine the branching fraction of the leptonic decay $D^+\to\mu^+\nu_\mu$ to be $(4.034\pm0.080_{\rm stat}\pm0.040_{\rm syst})\times10^{-4}$. Interpreting our measurement with knowledge of the Fermi coupling constant $G_F$, the masses of the $D^+$ and $\mu^+$ as well as the lifetime of the $D^+$, we determine $f_{D^+}|V_{cd}|=(48.02\pm0.48_{\rm stat}\pm0.24_{\rm syst}\pm0.12_{\rm input}\pm0.15_{\rm EM})~\mathrm{MeV}$ after taking into account necessary radiative corrections. This result is a factor of 2.3 more precise than the previous best measurement. Using the value of the magnitude of the $c\to d$ Cabibbo-Kobayashi-Maskawa matrix element $|V_{cd}|$ given by the global standard model fit, we obtain the $D^+$ decay constant $f_{D^+}=(213.5\pm2.1_{\rm stat}\pm1.1_{\rm syst}\pm0.8_{\rm input}\pm0.7_{\rm EM})$\,MeV. Alternatively, using the value of $f_{D^+}$ from a precise lattice quantum chromodynamics calculation, we extract $|V_{cd}|=0.2265\pm0.0023_{\rm stat}\pm0.0011_{\rm syst}\pm0.0009_{\rm input}\pm0.0007_{\rm EM}$.

With a modified chemical potential dependent effective model for the gluon propagator, we try to locate the critical end point (CEP) of strongly interacting matter in the framework of Dyson-Schwinger equations (DSE). Beyond the chiral limit, we find that Nambu solution and Wigner solution could coexist in some area. Using the CornwallJackiw-Tomboulis (CJT) effective action, we show that these two phases are connected by a first order phase transition. We then locate CEP as the end point of the first order phase transition line. Meanwhile, based on CJT effective action, we give a direct calculation for the chiral susceptibility and thereby study the crossover.

A simple prototypical model of aromatic pi-pi stacking system -- benzene sandwich dimer is investigated by ab initio calculations based on second-order Moller-Plesset perturbation theory (MP2) and Minnesota hybrid functional M06-2X.

Searching for two-dimensional (2D) organic Dirac materials, which have more adaptable practical applications in comparing with inorganic ones, is of great significance and has been ongoing. However, only two kinds of these materials with low Fermi velocity have been discovered so far. Herein, we report the design of an organic monolayer with C$_4$N$_3$H stoichiometry which possesses fascinating structure and good stability in its free-standing state. More importantly, we demonstrate that this monolayer is a semimetal with anisotropic Dirac cones and very high Fermi velocity. This Fermi velocity is roughly one order of magnitude larger than that in 2D organic Dirac materials ever reported, and is comparable to that in graphene. The Dirac states in this monolayer arise from the extended $\pi$-electron conjugation system formed by the overlapping 2\emph{p}$_z$ orbitals of carbon and nitrogen atoms. Our finding opens a door for searching more 2D organic Dirac materials with high Fermi velocity.

To obtain high-performance spintronic devices with high integration density, two-dimensional (2D) half-metallic materials are eagerly pursued all along. Here, we propose a stable 2D material with a honeycomb-kagome lattice, i.e., the Mg3C2 monolayer, based on first-principles calculations. This monolayer is an anti-ferromagnetic (AFM) semiconductor at its ground state. We further demonstrate that a transition from AFM semiconductor to ferromagnetic half-metal in this 2D material can be induced by carrier (electron or hole) doping. This magnetic transition can be understood by the Stoner criterion. In addition, the half-metallicity arises from the 2pz orbitals of the carbon (C) atoms for the electron-doped system, but from the C 2px and 2py orbitals for the case of hole doping. Our findings highlight a new promising material with controllable magnetic and electronic properties toward 2D spintronic applications.

A search has been performed for the semileptonic decays $D^{0}\to K_{S}^{0} K^{-} e^{+}\nu_{e}$, $D^{+}\to K_{S}^{0} K_{S}^{0} e^{+}\nu_{e}$ and $D^{+}\to K^{+}K^{-} e^{+}\nu_{e}$, using $7.9~\mathrm{fb}^{-1}$ of $e^+e^-$ annihilation data collected at the center-of-mass energy $\sqrt{s}=3.773$ GeV by the BESIII detector operating at the BEPCII collider. No significant signals are observed, and upper limits are set at the 90\% confidence level of $2.13\times10^{-5}$, $1.54\times10^{-5}$ and $2.10\times10^{-5}$ for the branching fractions of $D^{0}\to K_{S}^{0} K^{-} e^{+}\nu_{e}$, $D^{+}\to K_{S}^{0} K_{S}^{0} e^{+}\nu_{e}$ and $D^{+}\to K^{+}K^{-} e^{+}\nu_{e}$, respectively.

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD systems encounter limitations. Specifically, while CAD systems can achieve high performance in the detection of lung nodules, they face challenges in accurately predicting multiple cancer types. This limitation can be attributed to the scarcity of publicly available datasets annotated with expert-level cancer type information. This research aims to bridge this gap by providing publicly accessible datasets and reliable tools for medical diagnosis, facilitating a finer categorization of different types of lung diseases so as to offer precise treatment recommendations. To achieve this objective, we curated a diverse dataset of lung Computed Tomography (CT) images, comprising 330 annotated nodules (nodules are labeled as bounding boxes) from 95 distinct patients. The quality of the dataset was evaluated using a variety of classical classification and detection models, and these promising results demonstrate that the dataset has a feasible application and further facilitate intelligent auxiliary diagnosis.

In this study, we uncover the intrinsic information processes in non-Hermitian quantum systems and their thermodynamic effects. We demonstrate that these systems can exhibit negative entropy production, making them potential candidates for information engines. We also identify a key informational quantity that can characterize phase transitions beyond the reach of traditional partition functions. This work enhances our understanding of the interplay between information and thermodynamics, providing a new perspective on non-Hermitian quantum systems.

In this work, we propose a novel deformable convolutional pyramid network for unsupervised image registration. Specifically, the proposed network enhances the traditional pyramid network by adding an additional shared auxiliary decoder for image pairs. This decoder provides multi-scale high-level feature information from unblended image pairs for the registration task. During the registration process, we also design a multi-scale feature fusion block to extract the most beneficial features for the registration task from both global and local contexts. Validation results indicate that this method can capture complex deformations while achieving higher registration accuracy and maintaining smooth and plausible deformations.