Modern science advances fastest when thought meets action. LabOS represents the first AI co-scientist that unites computational reasoning with physical experimentation through multimodal perception, self-evolving agents, and Extended-Reality(XR)-enabled human-AI collaboration. By connecting multi-model AI agents, smart glasses, and robots, LabOS allows AI to see what scientists see, understand experimental context, and assist in real-time execution. Across applications -- from cancer immunotherapy target discovery to stem-cell engineering and material science -- LabOS shows that AI can move beyond computational design to participation, turning the laboratory into an intelligent, collaborative environment where human and machine discovery evolve together.

Computer-using agents (CUAs) must plan task workflows across diverse and evolving applications, yet progress is limited by the lack of large-scale, high-quality training data. Existing datasets are narrow, static, and costly to annotate, while synthetic data often yields oversimplified or misaligned behaviors. We present Watch & Learn (W&L), a framework that converts readily available Internet videos of human computer use into executable UI trajectories at scale. Instead of directly generating actions or relying on handcrafted heuristics, we cast trajectory annotation as an inverse dynamics problem that predicts user actions from consecutive screen states, which simplifies learning and generalizes across domains. Through a task-aware retrieval and labeling pipeline, W&L yields over 53K high-quality trajectories that enhance CUAs both as in-context exemplars and as supervised training data. On OSWorld, it consistently improves general-purpose and specialized CUAs, while on WindowsAgentArena it achieves state-of-the-art performance among 7B-scale models under the 15-step limit. These results show that web-scale human demonstration videos can serve as a practical and scalable foundation for advancing real-world CUAs.